Chronic Inflammatory Response Syndrome (CIRS) is a collection of symptoms which is also sometimes referred to as Biotoxin Illness, or Mold Illness,  and was initially thought to be caused by mold exposure only. However, further research indicates bacteria, fungus and various viral infections are also implicated in the development of Chronic Inflammatory Response Syndrome.

It is quite a dilemma for both patients and physicians in dealing with such a complex illness as CIRS,  which overlaps and can mimic symptoms associated with other conditions such as  Lyme Disease, Ehrlichiosis and some  Auto Immune Disorders. CIRS may often be misdiagnosed, or under diagnosed.

CIRS General Signs & Symptoms

Fatigue, weakness, flu-like symptoms, exhaustion, insomnia, sensitivity to environment, and possible multiple diagnoses from various doctors. 

Eye/Ear/Nose/Throat Symptoms
Blurred or hazy vision, eyes sensitive to light, eyes tear easily, , puffy/dark circles below the eyes, night blindness, ringing in the ears, hearing loss, dizziness, sinus/nasal congestion, nose bleeds, sensitive to odors, vocal cord polyps, nasal polyps, laryngitis or raspy voice, burning in the throat, or sore throat

Musculoskeletal Symptoms
Joint pain, shooting pain, ice-pick sharp pain, burning pain, stabbing pain, muscle cramps, muscle aches, muscle weakness, fleeting pain/pain that moves around, tics, spastic muscles, charlie horses, hands curl up like a claw, toes/feet curl up, morning stiffness

Lungs/Heart Symptoms
Shortness of breath and tachycardia (fast heart beat) with exercise, cough, wheezing, asthma, swelling or edema, heart palpitations, heart pounds intermittently

Digestive/Liver/Urinary Symptoms
Metallic taste in mouth, bile reflux, nausea, vomiting, diarrhea, constipation, abdominal pain, weight loss, weight gain, urinary frequency

Nervous/Endocrine/Immune Symptoms
Insomnia, headache, dizziness, mental confusion, poor concentration, poor short-term memory, forgetfulness, can’t remember names or words, poor word recall, disorientation, decreased learning ability, extreme thirst, low blood pressure, poor body temperature regulation, numbness, tingling, tremors, vertigo, Parkinson's-like symptoms, mood swings, anxiety,  irritability,  lack of sex drive, swollen and painful lymph nodes

Skin Symptoms
Skin is sensitive, skin is itchy, feels like bugs crawling on skin, feels like bugs stinging or biting but there is nothing there, easy bruising, Itchy pimples, skin sores, bumpy skin, thickened skin, skin peeling, burning sensations, red face, sweats - especially at night, static shocks, skin reacts to sun, even through clothing sometimes, vitiligo, cherry hemangiomas, and urticaria, commonly known as hives


Cold hands/feet, discolored hands and feet such as white and red mottling, numbness in parts of the body, e.g. foot  "goes to sleep",  tingling, hands shake, and clawing of fingers or toes

If you have any of the above symptoms and you have sought medical treatment with no significant results we encourage you to make an appointment with a Chronic Inflammatory Response Syndrome physician, CIRS specialist, Dr. Sherif Hassan.


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Lyme Disease and Co-infections

Case Study for Lyme and CIRS